In the few times I've seen this, it was from overcrowding and was believed to be from a bacterial infection. I'm not sure how clean you keep your cages, but in overcrowded conditions excess urine can create a wet substrate and mice can develope a condition know as 'wet-tail'. In all cases of prolapse I've seen, they had wet-tail. I'm not sure that is the true cause, but it makes the most sense considering how mice defecate. And you did the right thing by getting rid of them. It's not something that can be treated.....that I know of. Good luck.
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