I just got my first bite about a week ago. It was my 5 foot, 2500 gram girl that is not aggressive at all. I wasn't feeding her enough (2 small rats is not enough for this huge girl), and she wanted to let me know...lol. I hve several 'dots' on my arm from where her teeth dug in & a bruise. But it honestly didn't hurt anywhere near as much as I thought it would. Also, I placed my arm under running water to get her to let go. Worked like a charm.