I mist and it works better than without. I add a thin layer of pellets, MIST (not spray, mist), wait a few minutes and then add the rodents. It really cuts down on the smell and the dust. When I tried it with regular pellets, it was always extremely dusty, which is not good for rodents. If you're changing the bedding like you're supposed to, it doesn't cause any problems. Regular pine is bad for small critters, but, kiln dried is fine, and the pellets are pressed sawdust basically, and don't have the same natural oils in them any longer.
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