Watch the cats....I mean that literally. Watch them and see if they can find the snake for you. If they show particular interest in some little opening or tucked-away spot or under some furniture or something. And in the meantime, you may have to try to block the cats out of the room you think is most likely to be in when you can't be there to watch. If that isn't feasible, then just hope they don't find it before you do.
How big is Queen?