I dont see any reason a healthy gecko couldn't be handled daily. The only downside is some are a bit flighty, but almost all will calm down with a bit of handling. I have one particular gecko that I swear enjoys it. When I open his cage he comes right over to me and walks onto my hand. I always give him a little food and let him crawl around on me while I feed. The only downside is babies are tiny and fragile, and a lot of them have a tendency to crap on you if you keep them out for more than a couple minutes.