In my leo's enclosure, I put paper towels on half and have some tile in the other half. My leo seems to normally poop on the tile, so it is really easy to just pick out the dirty tile, replace it with clean ones, while I wash and sanitize the one that I took out. Then I replace the paper towel every week (unless it gets dirty then I replace it as needed).

To me, sand just doesn't seem worth it. I don't want to run the risk of impaction, plus it just seems so much harder to clean and to keep clean.