I don't have a ferret myself, but I work in a vet office. Most of the ferrets we see are older, and it is my impression that as they age they are rather prone to a variety of illnesses like adrenal disease and cancers. Most of the ferrets with problems we see are older. I believe it is less a husbandry issue and more a genetics thing. I would recommend reading Ferrets for Dummies. I read it a while back when my room mate got her ferrets and it is very informative.
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