I too get those migraine headaches if I use any of the artificial sweetners. One point I wanted to make that even though some chemicals are bad in large quantity, they can be very beneficial in smaller quantities. Flouride comes to mind as one example, and a more extreme case would be chemotherapy.

Anyway, if you were diabetic I think that the advantages would outweigh the cons of taking such a substance. Everything needs to be taken into account for your particular circumstances.