Im using a 30 gallon glass tank with cypress mulch and it really keeps the humidity up. I also have 3/4 of the screen top covered that I read in a sticky on the site. As far as misting I mist everything. I treated the piece wood I have with Deft. Its a sealer that is used on house furniture like tables and stuff. If you treat the wood just make sure it has plenty of time to dry. If you have any driftwood I would strongly recommend treating it with a sealer because it makes disinfecting it so much easier.