I won't spray anything in a room with reptiles or amphibians. I built activated carbon filters that are amazing. I got the filters for $40 at wormsway.com (CF-70?) and used them to build computer fan powered air filters. They last 18+ months before you have to change the filter, so they blow any Hepa or Ulpa filter away in price, and work just as good. For $120 I got 5 years worth of clean and odorless air. You can also buy an HVAC transformer on eBay for under $20 and use a $2 piece of glass and a couple of metal strips to make an ozone generator that will last forever without ever having to change a filter. If you use one of these in a room with animals it has to be on a timer to go on for a few minutes every hour or two, because ozone can cause damage to lung tissue. Other than that it is safe and works great. But you realy can't beat the $40 carbon air filters.