My Dad lives there. I love Vegas. Not sure what to avoid as I haven't been there in a long time. My fav. when I was a kid was Circus Circus, and the Big dome, I forget what its called but it has a roller coaster in it. Also my Dad said Mandalay Bay is really cool too.
Oh and you have to go to the space needle, or whatever its called, there is one in seattle too but I think the one in Vegas is bigger. Either way, its awesome being up that high and seeing the view.
While in Seattle go to the Aquarium if you get the chance.
As far as Vegas goes, I will email my Dad and see if there are any cool events happening while you will be there. When are you supposed to be in Vegas?