I had it happen to me last year. I shipped a pair of Axanthics to California. The temps were perfect for the entire trip, and no heat or cool packs were required. I shipped Delta Dash. The box got to Atlanta, and missed the connecting flight. It then got to California late, where the Delta agents had told my customer he would have to come back the next morning (which is completely wrong, as he can claim it in the baggage area). The next morning I got a call that informed me the female Axanthic was DOA. It appeared that she had overheated. I think the box was left in the sun in Atlanta. I then proceeded to box up another female Axanthics and send her on her way. The second one made it fine.
p.s. Getting claims money from Delta is next to impossible, even after I appealed twice. Don't expect to get anything from their insurance policy.