When a 6ft burmese python mistook my hand for a rat, I remembered the alcohol trick. All I had was a drunk snake with a taste for more blood. That time, someone else had to pry the teeth out of my hand and peel it off from around my wrist.
The second time he was nearly 9ft long and he was in shed (I guess he thought I was a rat again). Not my proudest moment, to have it happen a second time. My wife heard a loud THUMP and a "F***! HEY, TURN THE TUB ON HOT!"
I dragged this 9ft python into the bathroom, put his head under the hot water, and he INSTANTLY let go. INSTANTLY. This time the little puncture wounds healed very quickly because it was only pin pricks versus trying to rip 100 gripping teeth out of your flesh. That first time I hurt for about a month. This time it only hurt for a day.
So, hot water in the face is my vote for the best way to handle a constriction.
And I haven't been bitten since, just fyi. It's all about gloves, tongs, and brains.
Hope this helps.