Brad nailed it.

Even with all of the captive breeding being done, we don't even come close to producing the numbers being imported into the US each year. It will be a long time before captive production can meet the demand for these animals.

On top of all that, the import and export of p. regius is regulated by an international body called the "Convention on International Trade in Endangered Species of Wild Fauna and Flora" or CITES ... they set the quota for the number of exports leaving each country in West Africa every year based on the numbers of ball pythons in the wild. It's there job to make sure ball pythons (and all animals under their umbrella) are farmed in a way that does not impact wild populations.

Wild ball pythons are well protected.

-adam