We put them in a completely seperate room of the house nowhere near the room where the rest of the snakes are. We take care of the established snakes first, as far as cleaning, feeding, handling, etc. then do any in quarantine. The two groups have no contact at all ever. If you feed f/t then your snakes in quarantine need a seperate set of feeding tongs. If you have a snake in quarantine for say 10 days and add in another new snake, you reset the time back to day 1 for all the snakes in the quarantine area.