Did this happen right after you picked him up? Is it possible that he'd just been drinking and some water dribbled out of his mouth?


Otherwise, no, snakes don't drool unless something is wrong. Either an RI causing mucus buildup or a mouth infection. No one can diagnose over the Internet, though, and unless you're certain he was dribbling water he'd just drunk, I'd make a vet appt to have him checked out.