The crosses? Nope, not that I know of. I have three of them, two hets and the albino female above, and they are all just as healthy as any other boa I have. They just look prettier is all. When lines are crossed in nature they usually prosper in health. Look at the mule. It seems that only the best qualities pass on to the siblings. This isn't proven by any stretch of the imagination, but it sure does look that way. I got the above Female and the pair of hets from Mike at Basically Boas. He has been working with perfecting the best looking albinos for many years now and he hasn't reported any problems with them either.