I wouldn't imaging you'd have to put holes in the box.

The heat packs are in case you're shipping somewhere cold. I believe it's vice versa for somewhere hot...Never heard of anyone putting a hot and cold pack in...so i don't know if it's done.

When you ship, it's ideal to make sure the shipment will arrive next day, as early as possible. That's why avg. shipping is about 50 bucks per shipment.