I go away all the time for usually in the 5-6 day span.
If I go for that long I have a friend who lives close by who comes in to feed and water the cat so he checks on my bp ie checks temps, that everything is good and no bulbs burned out or heat cable, T-stat working.
He also will swing by in the event we have a storm to double check the breakers/elec in the house and in Ozzy's cage.
He doesn't open the cage or change water and he knows in the event something wrong to call me and I will instruct him from there.
If Ozzy needed to go to the vet etc he wouldn't have a problem and knows how to get him out and transport him. He is not a snake person but I have instructed him well and now he is an old pro.

If I go away for a weekend I just make sure he has water and the cage is locked, double check his cage settings and the heat/ac settings in my house.

I leave my friend a cheat sheet with all settings etc on it and diagrams of everything.

I still worry