I keep mine at my office..and I work with a Hip Hop/Mixtape Company [www.mixtapecorner.com] ... so there is usually alot of music playing throughout the day. It doesnt really seem to bother her... not even enough for her to come out and play
.. BUT.. she's a huge ham and loves to come out when she see's the flash on my camera.. lol

either way..unless u have the enclosure directly next to the speakers, drums, etc.. i doubt it would be an issue. because the only way the snake would really get irritated by the vibrations is if it were directly feeling the thump.