Are these new behaviors concerning or am I just being paranoid?

[Homebody]

She's been moving her head and neck strangely. Before anyone becomes alarmed, no she's not stargazing. Her head isn't going up and back for long periods of time and she's not having issues keeping balance. But for some reason, she'll lift her head up and move it around to sniff things, but when she does her head moves in a sort of twitchy or jerky motion. It looks somewhat mechanical and robot-like if that makes sense. Her head also seems to bob and shake sometimes as well. She also does this thing where she contracts her neck into an S shape for a minute, and then she starts squeezing and contracting the muscles in her neck so hard that she starts to shake. She stops after doing that for a minute and then hangs out for a minute, and then repeats the whole cycle.

That would concern me too with all the chatter about neurological diseases affecting pythons. A video of the behavior would be helpful. You describe the behavior very well, but I hesitate to reassure you without seeing the behavior for myself. This thread has instructions on how to post video.

As for the increased activity, pics of your set up along with your temperature and humidity readings would help us identify any issues that may be distressing your snake. For instructions on how to post pics, see this thread.