I'm a bit confused by the mucus on the eye part...
Was it mucus from her mouth? Because ball pythons have a scale layer of protection over their eyes so they aren't 'moist' unless something severely damages the eye itself. Her eyes are beautiful. Was it maybe the blue haze they get before shedding making her look cloudy? Sometimes they do wheeze a bit before a shed.
If we can see pictures of the whole setup, it might help. The little bit of substrate I can see looks almost like a coco fiber and chip mix? The fiber is fine enough to lodge in her nostrils and irritate them a bit if she's really pushing. It definitely looks like she's rubbing because I can see two small marks on her forehead. Her heat pits are a more normal looking color to me because her nose is so pale. If it looks more red at times it can be because of the pushing and rubbing.
I agree with Bogertophis that if you are concerned, there is only so much advice we can give on a medical area and a vet is the best option.