I personally wouldn't use Frontline but I know others do. I prefer PAM (Provent a Mite). Since Natural Chemistry was also mentioned, I just wanted to remind any newer keepers that any substance - 'natural' or not - that is capable of killing mites is also capable of killing your snake or causing neurological damage if not used correctly. In a keepers group I admin, we had an instance just last month of a young snake having seizures after the keeper used Natural Chemistry on it. It turns out he was spraying most of the damned bottle on the poor animal.
You have to use some pretty nasty stuff to successfully eradicate a mite infestation - there's no getting around it. So just please please be very careful, don't put mite products directly on very small, very young, or debilitated snakes, don't overuse the product, and when used on enclosures be absolutely certain it has dried completely before putting the snake back in.
I wish the predatory Taurrus mites were available in the U.S. for eradicating snake mites but for some reason we can't get them here. I know there are other predatory mites folks have tried but from the reports I've gotten they aren't as effective as the Taurrus mites.
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