I have two female ball pythons with the spider gene (mother-daughter) and don't have to do anything different for them regarding husbandry other than they never get a live feeder. They do wobble quite a bit when excited, like at feeding time, so their strikes tend to go everywhere except toward the feeder. I get the f/t feeder close enough to their noses so they can't miss it, and after that they're fine.
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