Hey, I'm just offering some discussion, not the "last word", lol.And happily I've only dealt personally with mites TWICE, both times were many years ago. I've been keeping many snakes for a lot of years, & it's shocking to see how prevalent mites & some herp diseases have become. I feel statistically very lucky, but these days I don't go to expos, & rarely to pet stores- "risky" places.
Might be a way to follow your suggestion more safely- I dislike aerosols anyway- they go everywhere. Maybe spray it onto a sponge (inside an open box outdoors, to help contain it), then wipe the sponge on the floor (& wearing rubber gloves). I wonder if that's really enough exposure though, to prevent mites from crossing the "barrier"? Full disclosure, I really dislike using pesticides- I avoid them 99.9% of the time. They have a way of biting our own health too.
And your perimeter treatment still won't keep out airborne pathogens, even if it works for mites.