It can be hard on the kidneys to feed your snake too much food. Post a picture of your snake and the prey item and we could better answer your question. It depends on how big the mouse is also the thing is when snakes go off food you don't want to overfeed them when they decide to go back to eating. It can overload the kidneys and I have heard from reputable breeders that if you try to feed them more than one prey item after a large length of time in between meals they can die.