Besides looking into her nostrils with a mini-flashlight for debris & carefully removing it with fine-tipped tweezers (if you have them AND a steady hand, their nose is very
delicate) you might also try one of those soft rubber bulb syringes (like they sell with ear cleaning kits) to gently suck out each nostril? I think that would be quite safe,
not that she'll appreciate your efforts, lol. I'd also mist her or raise her humidity some.
If my guess is correct, she has either a little flap of old skin or debris that moves as she breathes, so sometimes she whistles & sometimes not. There are also some people who have said their snakes just always have a slight whistle, thought to be due to the snake equivalent of a deviated septum, but in yours this is a "new" symptom, so you have to play detective.
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