I use a blend of EcoEarth and ReptiBark. Been using it for years now. It holds humidity well, spot cleans easily, retains odor and looks naturalistic.
But like Deb mentioned above, there's no "one size fits all answer". What works for me in MASS might not work for others living in different climates, for example.
I personally don't like Aspen because I find it messy, it doesn't retain humidity well and honestly, I don't like how it looks. But that's ME.
Regardless of substrate choice, as long as it's reptile safe, it's important to keep it clean. Substrates don't cause scale rot or RI, improper husbandry and dirty enclosures do.