You do not.
Snake keepers do not need any more of the sort of media attention illegally bringing a giant python (or ANY snake) onto a plane would cause.
Appropriately labeled and through a carrier that does reptile shipping, a snake can be shipped via plane in the cargo area, but you would need to follow the proper rules for that including any registration if that is required (I do not know all of the rules for it offhand).
None of this "secretly" junk.
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