At a 130 grams your snake you be feeding on adult mice not hopper, hoppers are for snake out of the egg (generally weighing at 40 to 60 grams)
8 grams of weight loss is NOTHING hardly even a bowel movement. (that's 0.03 oz)
Yes she knows how to thermo-regulate they have done that without any help for millions of years the only thing they need from YOU is proper temperatures, however if the cool side is at 20 degrees you are not doing that and your temps are 4 to 5 degrees of. If your room temp does not allow you to reach 24 degrees as a minimum on the cool side, you need to provide supplemental heat to be able to do that.
As far as handling it depends on the animal and the younger/smaller the animal the more you want to limit handling, remember handling is for your enjoyment not theirs.
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