If she's new I wouldn't try handling right away. There needs to be established trust first for her sake. For the first few weeks when changing water or food just gently rub her with your finger while in the enclosure. Eventually she'll understand your not a threat and then it'll be easier to handle. Even still keeping handling to a minimum at first as to not stress her out. Baby steps will go a long way. The world is a big scary place to her and a big human is super scary. She'll come around in time with enough patience.
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