I bought a 3 year old female a few years ago who was fed live rodents her entire life, and I couldn't get her to switch to f/t after half a year (so I sold her). But I still fed her live every other time I prepped and offered her f/t, so that clearly didn't help lol.
I obviously can't say for sure whether she would be "impossible" to switch to f/t, but I know it would take many, many months of starving her of food first, maybe even a whole year. And watching her drop in weight. And not all owners are willing to do that and watch their snake grow thin just for the sake of f/t.
So you could say that some are impossible to switch to f/t, in a way. Especially adults that have always been fed live and some imports, like cheesenugget said.
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