I agree with the others about nose bleed, and do believe it’s worse depending on how you go about defrosting it. I prefer slowly over a couple of hours, then blasting with a hair dryer right before offering. I wouldn’t worry about a little ingested substrate, should be fine. Welcome to snake keeping, eventually if you’re really lucky you’ll get a mouse that explodes during constricting. Now that’s a real fine how do you do! Again probably a result of heating to quickly.
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