Im fairly new to this and I'm sure some others will reply who have much more experience than me but........... When you first bring them home you should wait to feed them for a while until they get acclimated to there new environment. They get stressed out very easily. Also when you said you tried to feed a mouse and left it in overnight I hope it wasn't a live mouse. Never leave a live mouse in the enclosure unattended as they can hurt the snake. I am sure people are gonna ask you for the following. What type of enclosure? What are your temp? How are you heating? How are you regulating your heat?
See above post. I was to slow