It definitely could be the reason, or at leaat be contributing to his stress.
In my experience it really depends on the animal when it comes to shed turning them defensive. For example, my Cal King, Django and my hognose, Cosmo are complete jerks in shed (every King I've kept has been though), but sweethearts otherwise. My BP, Tyson, however remains chill as can be even in shed. Yet my old BP was a nightmare in shed.
Just move forward as planned, keeping an eye on humidity and all should be good.









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