Depends on the substrate, but I'd rather my snakes do NOT ingest it...once in a while it can lodge in their mouth, for example, & cause irritation & infection.
Yes, they do ingest bits of stuff in the wild too, but these are our pets & presumably we want to prevent whatever problems we can foresee. I for one do not
enjoy trying to retrieve substrate stuck in a snake's mouth. Also, I believe that their digestive enzymes cannot digest wood, while they ARE designed to digest
bones & all that, so I'm siding with the OP on this: prevention.