It depends on the stripe itself for me. If it fades into the rest of the morph like on the potions I've seen I don't mind it. There is just something about a bold continuous stripe that looks off to me though. It's not even that it looks bad, just that my brain says the snake shouldn't look like that and it wigs me out a bit.
I mentioned pinstripe since it's the one I've noticed the most, but the feeling applies to a lot of similar morphs for me.