I vacuum my snake room all of the time with no visible reactions. Now that room only has adults in it (8 if them).
I also use the loud Dyson hand vacuum to get substrate out of the sliding door tracks. Obviously the doors are open when doing so. Sometimes a snake may be 8 inches away and they don’t react.
I vacuum the quarantine room where the baby/juvie Olive is as well. I’ve never seen her react either.
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