I have a female BP Miss Snow that is difficult to handle. I started offering her a paper towel roll before removing her from her enclosure. When she sees it she curls up into her ball and then I remove her. I watched a youtube video about how to deal with aggressive retics and applied it to her. After removing her from her enclosure I place her in my lap and don't touch her right away. After a few min she relaxes and starts to crawl away. While she is balled up I don't make fast motions or motions near her head or tail. Once she starts to crawl away, I just keep her within reach allowing her to crawl a bit. Then she will let me pick her up enough to put her back in her enclosure. She is learning slowly that I am none thing to fear. It has taken almost 3 months to get her adjusted to this method so it was not a quick process. She has bitten my girlfriend, another friend of mine, but not me. The difference is that when I have her, all my attention is on her. My other 2 BPs and RTB and retic are much easier to handle than she is but she is coming around.