Caramel, sure, as long as you (you as in - whoever is working with it) is prepared to deal with the possible issues of kinks and female lower fertility which might occur.
Desert* however, no, please don't encourage people to work with that gene. They make beautiful snakes but the females should not be bred. Here's a thread with more info, great link in the first post: https://ball-pythons.net/forums/show...Justin-Kobylka
*speaking of the Desert gene, not the Desert Ghost since they are not related. I really wish they had used a different name for DG![]()