Honestly depends on the animal.
Bought mine with the breeder candidly saying he DID skip weeks already on his own. When I first got him, he ate weekly for me. But now he's back to refusing for a week or two then wanting it on the second/third week.
I think a lot of it depends on the particular animal. My male is rather lean due to these self-imposed fasts but since May he's gone from about 34" long and in the mid 600s to 37" long and in the high 700s. Some males will eat weekly or more often, probably based on the prey weight to body weight ratio and tons of other factors. Some only one a small once a month.
I'm not doing it to save cash, it's more not to waste it since he's been regularly refusing bi-weekly, leading to me having to toss a rat. So, I've swapped him to a biweekly feeding for now. Maybe through the summer he'll go back to weekly.
I just make sure to observe him at night.
In his hide watching me/the GF? Not hungry.
On top of his hide nosing the lid/glass? Probably hungry. Try offering the following weekend.
So far it's been working for him.
As an addition, to stay topical: the reason the breeder held him back 'til he was 2 was PROBABLY due to this and the fact careguides often biblically set a "once a week small rat!" guide. Pollux is not doing that. The breeder didn't underfeed him by choice, nor have I.
Something to take into consideration when getting small adults.