If you feel the need to do something, it's safest to use a tepid water only rinse to clean you ball python.

On rare occasions (after egg laying for example) I use tepid water with a drop or two of a mild unscented hand soap but never above the snakes neck or on its head.

Shedding is the natural way for your snake to clean itself, if at all possible you should just let it occur naturally.

Hope this helps.

-adam