My method, lice medicine mixed with water, spray the snake, and use a q tip or your hand to get her eyes and heat pits, if you spray the snake and ypu put her in a small container (mine was a baby and i put him in a deli cup) so that all the mites get exposed its better, and i dumped his substrate, boiled his hide and water bowl, and bleached the cage. I did all of this the same day and after the bleach fumes were gone i put him back (after the treatment) and i never had to do it again, all the mites died