This is an interesting question as I've been reading a bit about the way that snakes sense things, and this would be more a question about the visual cortex of snakes than the actual action of the eye itself. Ball pythons in particular don't have the best eyesight, they rely a lot on heat signatures, vibrations and scents... but some have experienced them reacting to reflections in the way they would react to another snake. This signals that perhaps their visual cortex is more complex than I would expect... BUT this could be related to movement and recognizing the distinct way that another snake 'moves' and not so much the actual flat image of the snake.
I really feel that a flat image, especially a handmade one, would NOT affect the snake in any way whatsoever because it wouldn't connect the symbols to a specific thing. A photograph might be more likely to have any effect but even then I don't believe it would have any.
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