I've never had ball pythons together except for breeding, so can't give any personal insight. But if it's come into question then having it sexed wouldn't be a bad idea so you have piece of mind. If you've never sexed a snake before it would be best to take her to someone who has experience in it.
On a side note she looks gorgeous. Love that black spot! Is he just a unique pied or is there something else in the mix?