The one time my new girl wouldn't eat was because I thawed in water that was way too hot and pretty much cooked the mouse. I was just in a hurry. She wouldn't touch it. The next week and ever since she is back to being a garbage disposal. I don't thaw with water anymore. I let it thaw all the way naturally and then warm it up with a hair dryer and she nails them every time. Really trying to resist the urge to overfeed.