Not just holding, you can hold! It's caused by too low temps for too long, too high humidity with too little air flow, or too low humidity. Maybe combined with too frequent or too lengthy handling (maybe the environment outside the enclosure isn't as suitable), causes stress, which causes a poor immune system, which makes the animal more susceptible to infections or illness than it was before. Like people and other animals, stress worsens the immune system too. So it could be a combo of these things, all of these things, or just one...
KingWheatley's snake isn't a for sure respiratory infection yet since we're just talking online, but it sounds likely? Just watch for his mouth staying open again like that, bubbles in his mouth, any audible sounds when breathing, and will need a vet if those.









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