I had my ball python grab my finger after she thought it was a skinny rat and try and drag it into her hide to eat. That actually hurt lol. The only way I got her to let go was I had to pick up with my other hand and dunk her head and my finger in her water bowl. She then let go, looked up at, adjusted her jaw and crawled back into her hide lol. She is alittle over 4'. I've also had my sunglow boa spin around 180 and latch onto the webbing between my thumb and index finger once when I thought "meh, its ok to play with F/T rats and then reach in behind a snake" "No way they can spin around before I can get my hand out of the cage".....yes they canThat one kind of hurt too.