Interesting discussion! Most of my ball pythons have the spider gene in them, and I don't really notice much of a head wobble on hardly any of them at all. It's a very popular gene, I just looked on Morphmarket and they have sold + for sale a total of 2,248 snakes with the spider gene.
I think it really enhances the genetic study of these snakes. There are other genes that make snakes wobbly like the Champagne gene, or genes that produce mainly males or females like the Banana / Coral Glow gene. There are other combos that make snakes particularly aggressive, I'm pretty sure a spider + pastel seems to enhance the aggressiveness, maybe that's why they call them 'bumble bees' LOL. And the super cinnamons are also reported to be very aggressive by some of the pro breeders. I find the whole thing very fascinating. And we are now in a time where there are so many new gene combos that almost every week I see a snake that's a 'worlds first' combo of certain genes. And some of the paint jobs really surprise me, like the Mojave + GHI, a combo that looks completely different than both of the parents. And the allelic combos from two different co-dominant genes that act as a super producing no normals, now that blows me away!
I find it a very interesting study in genetics, especially since we started talking about different color patterns of the same species and found out how it really affects the animal on so many different levels.
Now if you want to talk about unethical, how about a super wobbly aggressive snake like a super cinnamon spider champagne! LOL