Run malwarebytes in safe mode with networking
After that runs its course, run the disk cleanup for windows ( https://support.microsoft.com/en-us/...-in-windows-10 )
Finally, defragment your computer.
That said, run Avast and AVG simultaneously as your antivirus software. Should keep you really protected.
Finally, get firefox, get the noscript addon and adblocker plus. With noscript you will have issues browsing the web, if you use a little sense you can safely allow certain things and the web should run fine. Never allow doubleclick or googleanalytics, though.
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